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human lymphoblastoid cell line panels  (Future Medicine Ltd)

 
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    Future Medicine Ltd human lymphoblastoid cell line panels
    Human Lymphoblastoid Cell Line Panels, supplied by Future Medicine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+lymphoblastoid+cell+line+panels/human+lymphoblastoid+cell+line+panels/pm20235789-19-12-4
    Average 90 stars, based on 1 article reviews
    human lymphoblastoid cell line panels - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    In Vitro:

    Article Title: Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways.
    Article Snippet: Need for in vitro tools for assessing in silico-generated drug target predictions Bioinformatics tools are becoming available for predicting drug targets and pathways, with numerous in silico approaches and increasingly powerful computational resources.. Such tools are indispensable for drug-development projects and may yield clues toward discovering pharmacogenetic biomarkers for improving drug safety and efficacy and minimizing drug interactions.. For example, the Connectivity Map at the Broad Institutecan be employed for finding connections between small molecules and predicting drug targets and pathways [1–3,101].

    In Silico:

    Article Title: Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways.
    Article Snippet: Need for in vitro tools for assessing in silico-generated drug target predictions Bioinformatics tools are becoming available for predicting drug targets and pathways, with numerous in silico approaches and increasingly powerful computational resources.. Such tools are indispensable for drug-development projects and may yield clues toward discovering pharmacogenetic biomarkers for improving drug safety and efficacy and minimizing drug interactions.. For example, the Connectivity Map at the Broad Institutecan be employed for finding connections between small molecules and predicting drug targets and pathways [1–3,101].



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    Knock down of VAV3 and GPM6A expression in human SU86 and Hup-T3 pancreatic cancer cell lines as well as lymphoblastoid cell lines showed increased resistance to gemcitabine and AraC after siRNA knock down as determined by MTS assays. Error bars represent SEM values for 3 independent experiments. Quantitative RT-PCR was performed to assess VAV3 and GPM6A gene expression levels after knock down with specific siRNAs. Results are expressed as % of control. Error bars represent SEM values for 3 independent experiments. * = p<0.05.

    Journal: PLoS ONE

    Article Title: Gemcitabine and Arabinosylcytosin Pharmacogenomics: Genome-Wide Association and Drug Response Biomarkers

    doi: 10.1371/journal.pone.0007765

    Figure Lengend Snippet: Knock down of VAV3 and GPM6A expression in human SU86 and Hup-T3 pancreatic cancer cell lines as well as lymphoblastoid cell lines showed increased resistance to gemcitabine and AraC after siRNA knock down as determined by MTS assays. Error bars represent SEM values for 3 independent experiments. Quantitative RT-PCR was performed to assess VAV3 and GPM6A gene expression levels after knock down with specific siRNAs. Results are expressed as % of control. Error bars represent SEM values for 3 independent experiments. * = p<0.05.

    Article Snippet: In a present study, we took advantage of ethnically diverse Coriell “Human Variation Panel” lymphoblastoid cell lines to test the hypothesis that genetic variation across the genome in germline DNA might impact gemcitabine and AraC cytotoxicity.

    Techniques: Expressing, Quantitative RT-PCR